STUDY
ON THIOPHENES EXTRACTION EFFICACY
FROM TAGETES
PATULA L.
Veronica DRUMEA[1], Brandusa
DUMITRIU[2], Ionut-Bogdan VOINICU[3]
Laura OLARIU[4]
Abstract. The species of the
genus Tagetes (family Asteraceae) known as ˝marigolds˝ are usually
cultivated as ornamental plants, but are also studied and valued for their
pharmacological properties in medicinal practice and for their biological
actions in agriculture. The antifungal effect of the extracts, thanks to the
content of thiophenes has been demonstrated in numerous studies. The study aims
to obtain a qualitative extract from Tagetes patula
L. (French marigold) with antifungal properties. The terthiophene in the
extract obtained from dried inflorescences of a cultivar of Tagetes patula L. has been assayed by gas-chromatography, based on
the calibration curve of the reference substance and has been compared to the
content of the vegetal product. The extraction yield of the identified
thiophenes, calculated as areas ratio between the extract and the plant, was
78%, while the median recovery ratio of the terthiophene (concentration in
plant 0.021%) was 90%. The content corresponds to a significant potential of the
antifungal effect of the extract.
Keywords: Tagetes patula, thiophenes, alpha-terthienyl,
extraction, GC-MS, SIM
DOI
https://doi.org/10.56082/annalsarscibio.2022.2.81
[1] BIOTEHNOS S.A., Gorunului Street No. 3-5,
075100 Otopeni, Ilfov, Romania. Address for
correspondence to: Veronica Drumea, e-mail:
veronica.drumea@biotehnos.com, phone: 031/710.24.02; 031/710.23.82; Fax: 031/710.24.00
[2] BIOTEHNOS S.A., Gorunului Street No. 3-5,
075100 Otopeni, Ilfov
[3] BIOTEHNOS S.A., Gorunului Street No. 3-5,
075100 Otopeni, Ilfov; University of Medicine and
Pharmacy Carol Davila , Bucharest, Romania
[4] University of Medicine and Pharmacy Carol Davila , Bucharest,
Romania; Academy of Romanian Scientists.